"Travel & Leisure" put out its annual list of the top U.S. cities to visit.  And for the first time since 2012, Charleston, South Carolina is NOT #1.

Charleston held the top spot for 12 straight years.  But 180,000 readers voted, and the new best city in America is . . . Santa Fe, New Mexico.

Santa Fe scored the highest thanks to its 300 days of sunshine, excellent food options, and natural beauty.  Charleston fell to #3 this year.

The Top 10 U.S. cities to visit in 2025 are:  Santa Fe . . . New Orleans . . . Charleston . . . Savannah, Georgia . . . Alexandria, Virginia . . . Honolulu . . . Greenville, South Carolina . . . New York City . . . Asheville, North Carolina . . . and Chicago, Illinois.

Santa Fe ranked 19th worldwide.  The world #1 went to central Mexico's San Miguel de Allende. 

Mexico City also made the Top 10 at #7